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The recent findings clearly demonstrate
2018-11-14
The recent findings clearly demonstrate the mutagenic effect of ribavirin on the HEV genome, which can lead to an emergence of distinct viral populations (Debing et al., 2014, 2016b; Gisa et al., 2015; Todt et al., 2016). These distinct viral populations resulted from ribavirin treatment failure may
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Most chemotherapeutic drugs used clinically evoke cell apopt
2018-11-14
Most chemotherapeutic drugs used clinically evoke cell apoptosis by inducing DNA damage. However, the high efficiency of DNA repair due to the overexpression of DNA repair proteins in cancer AS1404 cost reduces the drug efficacy significantly (Fink et al., 1996, 1998). For example, the expression l
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By showing that pancreatic ductal perfusion of Ad
2018-11-14
By showing that pancreatic ductal perfusion of Ad-Munc18b attained a sustained improvement of glucose homeostasis in T2D GK rats, our study raises the possibility of employing this strategy in human subjects by endoscopy as a potential treatment for T2D patients. Adenovirus, whose effects lasted epi
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As opposed to schwannomas other
2018-11-14
As opposed to schwannomas, other driver mutations have been identified in meningioma, but those are mutually exclusive of Merlin (Clark et al., 2013). In order to keep the genetic background consistent with schwannoma, we analysed only Merlin-deficient WHO grade I meningiomas. Comparative functional
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The work by recently published
2018-11-14
The work by recently published in presents a possible route to explain the complex interaction between genetics and environment through the exposure to violet light (VL) within a narrow band of 360–400nm. After the earlier reports on the potential role of the transcription factor Erg-1 in myopia p
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Tumor relapse after radiotherapy is a significant challenge
2018-11-14
Tumor relapse after radiotherapy is a significant challenge to oncologists. Tumor recurrence was generally due to radiation resistance, which was determined by both the intrinsic characteristics and the extrinsic microenvironment of cancer TAK-242 manufacturer (Frank et al., 2010). The unique stem
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br Experimental design materials and methods We investigated
2018-11-14
Experimental design, materials, and methods We investigated the growth of illegal settlements on the frontiers of urbanization in Mexico City using a combination of human observation (VGI) and remote sensing (see Fig. 2). A graphical abstract can be found in the associated publication [4]. In the
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In this analysis the PCI values
2018-11-14
In this analysis, the PCI values of less than 10 represent a uniform distribution of rainfall (i.e. low BLZ945 manufacturer concentration); the PCI values between 11 and 15 denote a moderate precipitation concentration; values from 16 to 20 denote irregular distribution and values above 20 represen
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br Developmental changes in executive systems Executive func
2018-11-14
Developmental changes in executive systems Executive functions (EFs), such as voluntary attention control, intentional response selection, or contextual framing of stimuli, serve to guide behavior, attention, and memory toward or away from predetermined goals. EFs interface with perceptual system
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While in some cases focal
2018-11-13
While in some cases focal perinatal cytotoxicity assay damage can elicit resilience as above, discrete ischemic events can also have secondary and more widespread consequences for brain function (Volpe, 2009). Some of these secondary effects may be part of the local adaptive response, while others
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br Introduction Exploding foil initiator system
2018-11-13
Introduction Exploding foil initiator system (EFIS) has excellent safety and reliability. It can be used in the case of intense radiation, high altitude electro-magnetic pulse and stray current [1,2]. EFIS has been widely used in military and non-military applications [3]. Since the conception of
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Es en ese contexto de producciones cient ficas
2018-11-13
Es en ese contexto de producciones científicas acerca de los cuerpos, y en respuesta UM171 las provocaciones del movimiento político, que la intersexualidad surge como tema de interés de un cierto número de investigadoras identificadas con la perspectiva feminista, que pasan a dedicarse al área de l
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Por otro lado frente al reto de desdibujar
2018-11-13
Por otro lado, frente al reto de desdibujar desde la geografía de los sentidos las duplas cognición y sensación, Rodaway (1994) insiste en que la percepción puede entenderse como un proceso que implica sentir y recordar, reconocer y asociar. Es por ello que considerar el mutuo condicionamiento de am
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br Methods The list of used reagents can
2018-11-13
Methods The list of used reagents can be found in Supplementary information. Results and discussion Conclusion We have devised a novel gold nanoparticle based colorimetric Metabolism Compound Library for the detection of E. coli bacteria in urine of UTI patients. The sensor was constructed
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contrataci n con los particulares
2018-11-13
contratación con los particulares para la prestación del servicio público de transmisión y distribución de electricidad, conforme interleukin lo establecido en el Decreto, se extiende a prácticamente todo el ámbito de la actividad, esto es, financiamiento, instalación, mantenimiento, gestión, operac
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