• Cholangiopathies are a group of rare diseases whose primary

  2019-06-28

  

  Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce

• External parties ability and willingness to fund health

  2019-06-28

  

  External parties\' ability and willingness to fund health interventions is also an important factor in how governments decide on their spending priorities. Historically, development partners have funded prevention and treatment for a key group of diseases. Furthermore, a diverse set of barriers prev

• HBV DNA levels are associated with clinically significant

  2019-06-27

  

  HBV DNA levels are associated with clinically significant pathological events, such as cirrhosis; therefore, changes in the serum levels of HBV DNA could determine a risk for hepatocellular carcinoma. For on-treatment follow-up, HBeAg loss/seroconversion is important during the nucleoside therapy fo

• All these receptors tightly control tissue homeostasis and a

  2019-06-27

  

  All these receptors tightly control tissue homeostasis, and any dysregulation of these ligand–receptor systems (mutations, overexpression, etc.) disturbs cell communication and leads to pathological situations. Bone formation and bone remodelling are then controlled by a large panel of cytokines and

• Introduction Schwannoma is a benign tumor of neuroectodermal

  2019-06-27

  

  Introduction Schwannoma is a benign tumor of neuroectodermal derivation that originates from Schwann Irinotecan what which cover the peripheral nerves [3]. Approximately 25–40% of all schwannomas occur in the head and neck. These tumors most commonly arise in the soft tissues of the head and neck

• br Tuberculosis remains a global

  2019-06-27

  

  Tuberculosis remains a global emergency and continues to present major public health challenges worldwide. The actual global burden of tuberculosis can only be estimated because no accurate data are available from national country programmes from of high tuberculosis endemic countries. The WHO 201

• Dyslipidemia is characterized by increased

  2019-06-27

  

  Dyslipidemia is characterized by increased total cholesterol, LDL-C, and triglyceride levels, and decreased HDL-C levels. However, the association of ApoA1 polymorphism with serum HDL-C level remains controversial. The polymorphisms of ApoA1+84 TC, but not MspI, are associated with serum HDL-C. The

• Since antithrombotic therapy for patients with AF is

  2019-06-27

  

  Since antithrombotic therapy for patients with AF is rapidly changing with the increasing use of dabigatran, rivaroxaban, and apixaban, some of the primary issues that will influence the future revision of various guidelines (HRS [Heart Rhythm Society], ESC [European Society of Cardiology], ACC [Ame

• br Homing of DTCs to the

  2019-06-27

  

  Homing of DTCs to the HSC niche The HSC niche is a complex microenvironment comprised of many cell types, including endothelial cells, adipocytes, osteoclasts, osteomacs, and pim kinase inhibitor of osteoblastic lineage [5]. A healthy HSC niche provides homing signals to healthy HSCs in order to

• Como ha destacado Leonardo Tarife o su

  2019-06-27

  

  Como ha destacado Leonardo Tarifeño, “su obra nace de un malestar con el mundo que se estetiza para revelarse, y en ningún caso para ocultarse o refinarse” (75). Este malestar, aunado al afán realista localizable en su trabajo produce una búsqueda de elementos para acercar al lector con diversas fac

• It is well known that the precipitation of solid cholesterol

  2019-06-27

  

  It is well-known that the precipitation of solid cholesterol monohydrate crystals from supersaturated bile is the first irreversible physical-chemical step in gallstone formation. To study the characteristics, metastable intermediates, and kinetics in the phase transitions of bile, a series of phase

• The increasing burden of NCDs poses an

  2019-06-27

  

  The increasing burden of NCDs poses an enormous threat to populations and health systems across the globe. The Sustainable Development Goals represent an important opportunity to integrate efforts to reduce the burden of NCDs and promote sustainable development. The recent identification of NCDs as

• Second although it is an important and biologically plausibl

  2019-06-27

  

  Second, although it is an important and biologically plausible refinement, risk-factor adjustment based on lack of access to improved water in rural areas and urban slums could be open to criticism, as the authors acknowledge. The imperfect relation between access to improved water and consumption o

• De esta poca son los primeros testimonios de la idea

  2019-06-27

  

  De esta época son los primeros testimonios de la idea de fundar un periódico en París: en una carta del 7 de agosto de 1848, Eugène Carpentier, futuro administrador de La Tribune des Peuples, le presenta INCB3344 Mickiewicz un presupuesto estimado de lo que costaría un periódico. De cualquier manera

• El Acu fero Guaran se extiende en el

  2019-06-27

  

  El Acuífero Guaraní se extiende en el territorio de cuatro países de América del Sur: Argentina, Brasil, Paraguay y Uruguay. Está localizado entre los paralelos 16° y 32° S y los meridianos 47° y 60° W, cubre una superficie de 1 087 879 km2, provee de agua Matrine molecular gran parte de la població

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