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All these receptors tightly control tissue homeostasis and a
2019-06-27

All these receptors tightly control tissue homeostasis, and any dysregulation of these ligand–receptor systems (mutations, overexpression, etc.) disturbs cell communication and leads to pathological situations. Bone formation and bone remodelling are then controlled by a large panel of cytokines and
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Introduction Schwannoma is a benign tumor of neuroectodermal
2019-06-27

Introduction Schwannoma is a benign tumor of neuroectodermal derivation that originates from Schwann Irinotecan what which cover the peripheral nerves [3]. Approximately 25–40% of all schwannomas occur in the head and neck. These tumors most commonly arise in the soft tissues of the head and neck
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br Tuberculosis remains a global
2019-06-27

Tuberculosis remains a global emergency and continues to present major public health challenges worldwide. The actual global burden of tuberculosis can only be estimated because no accurate data are available from national country programmes from of high tuberculosis endemic countries. The WHO 201
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Dyslipidemia is characterized by increased
2019-06-27

Dyslipidemia is characterized by increased total cholesterol, LDL-C, and triglyceride levels, and decreased HDL-C levels. However, the association of ApoA1 polymorphism with serum HDL-C level remains controversial. The polymorphisms of ApoA1+84 TC, but not MspI, are associated with serum HDL-C. The
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Since antithrombotic therapy for patients with AF is
2019-06-27

Since antithrombotic therapy for patients with AF is rapidly changing with the increasing use of dabigatran, rivaroxaban, and apixaban, some of the primary issues that will influence the future revision of various guidelines (HRS [Heart Rhythm Society], ESC [European Society of Cardiology], ACC [Ame
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br Homing of DTCs to the
2019-06-27

Homing of DTCs to the HSC niche The HSC niche is a complex microenvironment comprised of many cell types, including endothelial cells, adipocytes, osteoclasts, osteomacs, and pim kinase inhibitor of osteoblastic lineage [5]. A healthy HSC niche provides homing signals to healthy HSCs in order to
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Como ha destacado Leonardo Tarife o su
2019-06-27

Como ha destacado Leonardo Tarifeño, “su obra nace de un malestar con el mundo que se estetiza para revelarse, y en ningún caso para ocultarse o refinarse” (75). Este malestar, aunado al afán realista localizable en su trabajo produce una búsqueda de elementos para acercar al lector con diversas fac
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It is well known that the precipitation of solid cholesterol
2019-06-27

It is well-known that the precipitation of solid cholesterol monohydrate crystals from supersaturated bile is the first irreversible physical-chemical step in gallstone formation. To study the characteristics, metastable intermediates, and kinetics in the phase transitions of bile, a series of phase
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The increasing burden of NCDs poses an
2019-06-27

The increasing burden of NCDs poses an enormous threat to populations and health systems across the globe. The Sustainable Development Goals represent an important opportunity to integrate efforts to reduce the burden of NCDs and promote sustainable development. The recent identification of NCDs as
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Second although it is an important and biologically plausibl
2019-06-27

Second, although it is an important and biologically plausible refinement, risk-factor adjustment based on lack of access to improved water in rural areas and urban slums could be open to criticism, as the authors acknowledge. The imperfect relation between access to improved water and consumption o
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De esta poca son los primeros testimonios de la idea
2019-06-27

De esta época son los primeros testimonios de la idea de fundar un periódico en París: en una carta del 7 de agosto de 1848, Eugène Carpentier, futuro administrador de La Tribune des Peuples, le presenta INCB3344 Mickiewicz un presupuesto estimado de lo que costaría un periódico. De cualquier manera
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El Acu fero Guaran se extiende en el
2019-06-27

El Acuífero Guaraní se extiende en el territorio de cuatro países de América del Sur: Argentina, Brasil, Paraguay y Uruguay. Está localizado entre los paralelos 16° y 32° S y los meridianos 47° y 60° W, cubre una superficie de 1 087 879 km2, provee de agua Matrine molecular gran parte de la població
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Nesta perspectiva enquanto o governo Humalla anunciou
2019-06-27

Nesta perspectiva, enquanto o governo Humalla anunciou uma lista de novos projetos mineiros de valor superior DMOG U$ 41 bilhões, dados da Defensoría del Pueblo registraram 210 conflitos sociais em janeiro de 2015 no país, dos quais 140 de natureza socioambiental. Até meados de 2015, contabilizaram‐
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Tipiracil hydrochloride Acetazolamide was unable to relieve
2019-06-27

Acetazolamide was unable to relieve the headaches and was discontinued. Topiramate was initiated, with subsequent headache relief noted at a dose of 100mg orally twice daily. With this therapy, ATRA was able to be re-titrated to a maximum of 40mg orally twice daily (80% of initial dose) over two wee
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Comparative data on the clinical presentation and
2019-06-27

Comparative data on the clinical presentation and outcome in NmC and NmA are scarce. In a brief report from northern Nigeria in 1977, 114 patients with meningococcal infection were studied, of whom 72 patients had NmC infection and 42 patients had NmA infection. All patients who Retaspimycin hydroc
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