• Repurposing use of approved drugs for new

  2019-05-17

  

  Repurposing (use of approved drugs for new indications) or repositioning (use of drugs whose development was not continued for new indications) of existing drugs has been put forward as a method to overcome some of these issues. Indeed, drug repositioning and repurposing could lead to higher rates o

• Ya en el siglo xx la Historia verdadera y

  2019-05-17

  

  Ya en el siglo xx, la Historia verdadera (y las crónicas de Indias en general) ha sido recuperada como origen de la literatura latinoamericana contemporánea, en especial por escritores vinculados Erlotinib la literatura del boom: Alejo Carpentier, Gabriel García Márquez, Carlos Fuentes. De hecho, Fu

• br Introduction Bone marrow adipocytes

  2019-05-16

  

  Introduction Bone marrow adipocytes are one of the most abundant cell types found in bone marrow tissue. They constitute approximately 15% of the bone marrow volume in young adults, rising to 60% by the age of 65 years old [1]. Previously considered as inert space filling cells with little biolog

• br Therapy for the CPVT

  2019-05-16

  

  Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele

• The excellent birth cohort study reported in by Heather Zar

  2019-05-16

  

  The excellent birth cohort study reported in by Heather Zar and colleagues, done in a periurban area outside Cape Town in South Africa, is a good example of a study that has provided important information about child pneumonia at a time of change. It provides the first incidence estimates of pneumo

• br Material and Methods br Results br

  2019-05-16

  

  Material and Methods Results Discussion Radiofrequency ablation has a long history of use. It has been used especially in the neurosurgical field [8,9]. Rosenthal described the first ablations in bone 20 years ago [5]. Technically the radiofrequency generator forms an electric current leadi

• An enhanced T wave suppression

  2019-05-16

  

  An enhanced T wave suppression mode was very effective to manage TWOS and was able to detect induced and spontaneous VF correctly. On the other hand, it has been reported that Biotronik devices connected to integrated bipolar ICD leads from other manufacturers had an increased risk for oversensing [

• La ignorancia que evidencia Xa Am

  2019-05-16

  

  La ignorancia que evidencia Xa. América poética respecto de los literatos mexicanos corrobora la falta de proximidad entre zonas tan distantes del orbe hispanoamericano. Al mismo tiempo comprueba el vacío biográfico que en este punto muestran las revistas mexicanas o, más exactamente, El Recreo de l

• br Epigenetic regulation of genes involved in hepatic lipid

  2019-05-16

  

  Epigenetic regulation of genes involved in hepatic lipid metabolism by S1P and SHP The signaling cascade of CBA > S1PR2 > SphK2 > S1P > HDAC1/2 > increased hepatic gene expression can differentially up-regulate blocks of genes involved in the hepatic metabolism of sterols and lipids (Fig. 3, Tabl

• A partir de las consideraciones que distinguen la institucio

  2019-05-15

  

  A partir de las consideraciones que distinguen la institucionalización formal e informal, O’Donnell hace un llamado Subjects tener en cuenta las especificidades de las democracias de América Latina y plantea que algunas democracias han subsistido, se han mantenido en el tiempo aun con la presencia d

• An anteroposterior AP radiograph of the pelvis and lateral r

  2019-05-15

  

  An anteroposterior (AP) radiograph of the pelvis and lateral radiograph of the right hip demonstrated moderate degenerative changes of both hips (Figs. 1 and 2). A provisional differential diagnosis of early avascular necrosis (AVN) or femoroacetabular impingement (FAI) was made. Renal function and

• lysophospholipid receptor br Materials and methods br

  2019-05-15

  

  Materials and methods Results We observed 3 patterns of response to PHP. Pattern 1, observed in 56% of patients (nos. 4, 6, 7, 8, and 9), was characterized by S–A and V–A intervals in the septal region that were identical whether HB was captured or not, along with an unchanged atrial activatio

• Sephin1 br Case A year old Caucasian male with a history

  2019-05-14

  

  Case 4 A 59 year old Caucasian male with a history of chronic renal insufficiency was transferred to our intensive care unit from an outside hospital, intubated secondary to respiratory failure and severe mucositis. He arrived on multiple broad spectrum Sephin1 for treatment of healthcare associ

• Next we evaluated the interatrial and interatrioventricular

  2019-05-14

  

  Next, we evaluated the interatrial and interatrioventricular synchrony because a long contraction time between the right and left atria was observed during the SSA procedure, dissection of the atrial septum, and patch closure. We were primarily concerned with determining whether the timing of the le

• br Conflict of interest br Introduction

  2019-05-14

  

  Conflict of interest Introduction Acute kidney injury in patients who are receiving anti-cancer treatments is an uncommon but serious complication. Such injury is often induced by nephrotoxic agents or urinary tract obstruction by space-occupying lesions. Among the many possible causes for ren

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