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The complex interplay between viral escape and Env conformat
2018-11-09

The complex interplay between viral escape and Env conformation observed by Bradley et al. and others gives some pause to reductionist approaches focussing on recapitulating single bNAb specificities by immunisation. Favourable voltage gated sodium channel interactions between different bNAb epitop
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As expected all pups of
2018-11-09

As expected, all pups of PBS-immunized dams showed neurological signs including loss of balance, paresis, and hindlimb paralysis, with 4.62±1.30 of neurological score. However, five out of six pups of MNA-ZIKV-rEfl-immunized dams exhibited neurological illness (no significant difference from the per
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Cy3 hydrazide The relative level of investment per death DAL
2018-11-09

The relative level of investment per death, DALY or YLD for all infections combined consistently increased over time (Tables 2–4). When considering time points 2004, 2010 and 2013, the median investment by mortality observed was £17.20, but greatest in 2013 (£31.16). HIV and malaria investments were
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br Method br Results br
2018-11-09

Method Results Discussion The fact that we did not see age and/or social-context dependent differences in NAcc engagement in response to the reward cue might seem surprising in light of some prior evidence indicating age differences in reward anticipation (e.g., Bjork et al., 2004; Galvan e
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br Materials and methods br Results
2018-11-09

Materials and methods Results Discussion The main metalloproteinase of the present investigation, that there is a positive association between IPS-to-prefrontal functional connectivity with age was largely not borne out, though positive trends were identified in ROI analyses in the younger
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We described the presence of dye and
2018-11-09

We described the presence of dye and electrical coupling in the RAS, specifically in the intralaminar parafascicular nucleus (Pf), the PPN, and the subcoeruleus dorsalis (SubCD), which modulates REM sleep [42–44]. We also found that the stimulant modafinil decreased the resistance of PPN, Pf, and Su
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br Results Anthropometrical measurements gestational age Apg
2018-11-09

Results Anthropometrical measurements, gestational age, Apgar score and delivery mode for all newborns are presented in Table 1. Wrist temperature presented clearly a dominant circadian rhythm for 7 subjects in their last week inside the NICU (the other 3 subjects showed a 12h rhythm as the most
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order PR-171 El tema ambiental es igual de complejo debido a
2018-11-09

El tema ambiental es igual de complejo, debido al alto crecimiento económico que ha registrado China, la demanda de bienes y servicios ambientales ha sido intensiva al igual que la generación de residuos y desechos. Lo cual afecta no sólo al territorio chino sino al resto del mundo ya que los países
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Las construcciones de carreteras transandinas unir
2018-11-09

Las construcciones de carreteras transandinas unirían partes apartadas y olvidadas de Perú, Bolivia y Colombia. La carretera interoceánica que une el estado brasileño de Rondonia con el departamento boliviano del Beni, constituyen los ejes andino y amazónico. Finalmente está la modernización de la v
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El crecimiento del comercio con
2018-11-09

El crecimiento del comercio con Estados Unidos se ha dado en un contexto de total apoyo oxytocin receptor las empresas extranjeras amparadas por la negociación del capítulo xi del tlcan, que da amplio margen de establecimiento a las empresas de los tres países, en condiciones de total asimetría con
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Cost effectiveness of varicella vaccination might be affecte
2018-11-09

Cost-effectiveness of varicella vaccination might be affected by several interacting factors. First, reducing VZV circulation by varicella vaccination might result in an increase in HZ incidence (Schuette and Hethcote, 1999; Brisson et al., 2000; Gidding et al., 2005; Karhunen et al., 2010) and an a
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The total OH D level was influenced by
2018-11-09

The total 25(OH)D level was influenced by genetic factors. In the current study, we found that rs7041, but not rs4588, influences the DBP level; however, both variants were significantly associated with the total and bioavailable 25(OH)D levels. A positive correlation was found between the circulati
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Thus various experimental approaches have been undertaken to
2018-11-08

Thus, various experimental approaches have been undertaken to determine the exact cellular origin of HSCs in different animal models. Constant cell labeling and time-lapse imaging performed during mouse ESC cultures and BL-CFC development have shown that the hemangioblast generates hematopoietic cel
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Introduction Human embryonic stem cells HESCs can differenti
2018-11-08

Introduction Human embryonic stem SW033291 (HESCs) can differentiate into the three embryonic germ layers and have the potential to develop into every cell in the human body (Thomson et al., 1998). In order to enable the clinical practice of HESC cell therapy it is essential to understand their di
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Many studies have demonstrated that
2018-11-08

Many studies have demonstrated that GSCs isolated from glioblastomas display a capacity for multiple-lineage differentiation (Hemmati et al., 2003; Matsuda et al., 2012; Singh et al., 2003, 2004; Sunayama et al., 2010b). When differentiated, these jak stat pathway usually lose the capacity for long
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