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A second and perhaps more philosophical implication of our f
2018-11-05
A second and perhaps more philosophical implication of our findings relates to the vital importance of social connections, trust and tolerance in our communities. These are hallmarks of social capital, and yet social, political and media commentary often laments their erosion in this modern era of s
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Aside from differences between countries differences
2018-11-05
Aside from differences between countries, differences also exist within countries. Indeed, recent research shows that in many African countries attitudes related to female genital cutting vary substantially at the individual and household levels (Bellemare et al., 2015; Efferson et al., 2015; Hernlu
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br Combinatorial approach for HEN
2018-11-05
Combinatorial approach for HEN of variable stream temperature The paths combination approach developed by Osman et al (Osman et al., 2009) is capable of generating a wider range of HEN retrofit solutions. Nevertheless, some solutions were found to be economically unjustifiable due to the long pay
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Other factors like the charge difference electronic distinct
2018-11-05
Other factors like the charge difference, electronic distinction and magnetic cytotoxicity assay are usually associated with the substitution of different cations with different sizes, so that their effects on the correlation pattern between the K and composition are hard to separate and much less
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br Immune profile of food allergy Despite the fact that
2018-11-05
Immune profile of food allergy Despite the fact that IgE plays a central role in the pathogenesis of food allergy, measurement of food-specific IgE is not diagnostic in isolation. Quantification of food-specific IgE antibody levels in serum can identify patients in the pediatric population who ar
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Previously it was shown th http www apexbt com
2018-11-05
Previously, it was shown that the Wnt1 transcript is strongly induced in MPTP-reactive astroglia, and the release of Wnt1 from these metalloproteinase was suggested (L\'episcopo et al., 2010, 2014b; Zhang et al., 2015). Our data show here that Dkk1-mediated blockade of the endogenous Wnt/β-catenin
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In their manuscript in Psomas
2018-11-05
In their manuscript in , Psomas and colleagues used a combination of 68 markers of immune activation and inflammation and two independent hierarchical clustering analyses to identify 5 donor groups from among 120 HIV-infected virologic responders (). These donor groups were characterized using combi
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glucokinase inhibitor Regions of linkage disequilibrium LD w
2018-11-05
Regions of linkage disequilibrium (LD) were defined for the three loci tagged by SNPs reaching genome-wide significance. rs17599026, associated with urinary frequency, tags a 106kb region of LD (base position 137,657,783–137,763,798; Fig. 2A) containing part of KDM3B (including the promoter region t
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Pro inflammatory and pro angiogenic factors are known to
2018-11-05
Pro-inflammatory and pro-angiogenic factors are known to be activated in the diabetic retina. Prominent among these are the inflammatory cytokine, interleukin (IL)-1β, tumor necrosis factor α (TNFα) and IL-6; the adhesion molecules ICAM1 and VCAM1; and the growth factor, vascular endothelial growth
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Deregulation of miRNA expression in cancer subsequently lead
2018-11-05
Deregulation of miRNA BLZ945 in cancer subsequently leads to altered functionality of these miRNAs. Upregulated miRNAs often act as oncogenes, as exemplified by miR-21 or miR-155 overexpression which causes acute B cell leukemia in transgenic mice models (Medina et al., 2010; Costinean et al., 2006)
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In this study we used a murine model
2018-11-05
In this study, we used a murine model of Schistosoma japonicum (S. japonicum) to investigate the roles of miR-146a/b, two upregulated miRNAs identified in our previous study (He et al., 2015), in the progression of hepatic schistosomiasis. We found miR-146 was primarily expressed in hepatic macropha
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Potentiation of the HDAC Pin signaling module
2018-11-05
Potentiation of the HDAC6-Pin1 signaling module by GRK2 in specific breast cancer cells could be envisaged as an adenosine deaminase to enhanced activity of different tumor-promoting cascades that would trigger a self-perpetuating positive feedback cycle promoting cell proliferation and increased s
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During CNTs synthesis the effects of synthesis
2018-11-05
During CNTs synthesis, the effects of synthesis parameters on the yield of CNTs produced were investigated using a 24 Factorial experimental design which was analyzed in Minitab ANOVA. The summary of the yield results obtained during CNTs synthesis is presented in Table 2. Results as presented indi
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ion channel Interestingly DBS in the medial
2018-11-05
Interestingly, DBS in the medial or intralaminar thalamus is being used with great success for the treatment of Tourette׳s syndrome [82,83]. One side effect of intralaminar thalamus DBS for Tourette׳s syndrome is profound fatigue. The parameters of stimulation typically include 24h stimulation at hi
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Introduction Duchenne Muscular Dystrophy DMD
2018-11-05
Introduction Duchenne Muscular Dystrophy (DMD) is an X-linked recessive neuromuscular disease. This fatal disease affects approximately 1:3,500 to 6,000 live male births [1] and 1:50,000,000 live female births [2,3]. It is a neuromuscular disorder characterized by a mutation in the dystrophin (DMD)
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