• For years FGF has been a requisite component

  2018-11-12

  

  For years, FGF has been a requisite component in human pluripotent stem cell media (Chen et al., 2011; Ludwig et al., 2006), and yet the mechanism by which FGF supports pluripotency was unknown. Our data show that ERK2, a downstream effector in the FGF pathway, directly phosphorylates NANOG at Ser52

• A number of important differences in gene

  2018-11-12

  

  A number of important differences in gene expression occurred with prolonged BMSC passage. Stem cell related genes, including Wnt and Notch signaling genes, were down-regulated in late passage cells. In addition, genes involved with DNA replication, recombination and repair, cell cycle, chromatin mo

• br Acknowledgments We thank Anke Leinhaas and

  2018-11-12

  

  Acknowledgments We thank Anke Leinhaas and Conny Thielen for excellent technical support. We thank the members of the histology laboratory of the Institute of Neuropathology, University of Bonn, for technical assistance with EB and teratoma staining and members of the Stem Cell Engineering Group

• Thus the persistent muscle expression

  2018-11-12

  

  Thus, the persistent muscle expression of full length dystrophin remains difficult to achieve currently. Since the discovery of satellite stem PR-619 Supplier and the difficulties met in maintaining their differentiation potential during in vitro culture, several promising alternative candidates fo

• The following are the supplementary related to

  2018-11-12

  

  The following are the supplementary related to this article. Acknowledgment We would like to thank for the financial support by the ALF Research Grant, Stockholm County Council; Chinese Scholarship Council, PR China; Craig Hospital Foundation, CO, USA; Magnus Bergvall Foundation, Svenska Läkarsä

• Partial cleavage of CXCL at the

  2018-11-09

  

  Partial cleavage of CXCL12 at the N-terminus by distinct peptidases results in loss of chemotactic activity and impairment in CXCR4 receptor affinity (Cho et al., 2010; Delgado et al., 2001; Levesque et al., 2003). The proteolytic cleavage of CXCL12 by matrix metalloproteinase 2 and 9 (MMP-2 and 9)

• Introduction Stem cells including neural stem cells

  2018-11-09

  

  Introduction Stem cells, including neural stem cells (NSCs), reside in specialized compartments that contribute to their maintenance. In the embryonic and adult mammalian brains, signals emanating from cells in the niche or the cerebrospinal fluid promote NSC self-renewal and proliferation (Lehtine

• br Results and Discussion br Experimental Procedures

  2018-11-09

  

  Results and Discussion Experimental Procedures Author Contributions Acknowledgments We would like to thank Hospital de São João for bone marrow samples and buffy coats. This work had the financial support of FCT/MEC through National Funds and, when applicable, co-financed by the FEDER th

• Introduction The mammalian respiratory tract is normally

  2018-11-09

  

  Introduction The mammalian respiratory tract is normally maintained by abundant progenitors that differ in molecular phenotype, differentiation potential, and regulation between airway regions along the proximodistal axis (Hogan et al., 2014; Rackley and Stripp, 2012). Basal cells maintain the pseu

• Introduction The mammalian respiratory tract is normally

  2018-11-09

  

  Introduction The mammalian respiratory tract is normally maintained by abundant progenitors that differ in molecular phenotype, differentiation potential, and regulation between airway regions along the proximodistal axis (Hogan et al., 2014; Rackley and Stripp, 2012). Basal cells maintain the pseu

• Fig a shows the tomogram obtained in the conditions when

  2018-11-09

  

  Fig. 2a shows the tomogram obtained in the conditions when the studied beeswax sample was placed in the following way: the sides of 17 × 8 cm and 14 × 8 cm were located, respectively, in the xz and yz planes, while the front face of 17 × 15 cm was in the xy plane. According to tomogram measurements,

• Then Eq can be rewritten in the following

  2018-11-09

  

  Then Eq. (3) can be rewritten in the following form, replacing the differentiation with respect to the dimensionless time by a variable dotted: Since the parameter T is arbitrary, let us set the following relationship between the newly-emerged multipliers: which separates the common multiplier o

• This evidence is in line with

  2018-11-09

  

  This evidence is in line with previous empirical investigations conducted on the UK with BHPS data by Giordano and Lindström (2011) and Lindström and Giordano (2016) which use active participation in associations as structural social capital and an index of self-rated psychological health obtained f

• It is important to consider the self construal of

  2018-11-09

  

  It is important to consider the self-construal of salespersons because the self-concept both mediates and regulates behavior. That is, the self-concept “interprets and organizes self-relevant actions and experiences; it dopamine-2 receptor antagonist has motivational consequences, providing the inc

• To evaluate the capacity of the newly

  2018-11-09

  

  To evaluate the capacity of the newly isolated recombinants to express BHV-1 UL49.5, total protein was isolated from virus-infected cells and analyzed by immunoblotting. BHV UL49.5 protein only accumulated in BV49.5-infected cells and was not detected in cells infected with the BV49.5-FS variant, wi

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