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br Introduction The mammary tissue
2018-11-02

Introduction The mammary tissue undergoes extensive morphological and phenotypic alterations during the pregnancy/lactation cycle forming a complex network of alveolar structures (Rosen et al., 1994; Macias and Hinck, 2012). This cellular architecture exhibits well defined A/B polarization establ
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Although WNT signaling plays a prominent
2018-11-02

Although WNT signaling plays a prominent role in A/P patterning of the neural tube, few studies have extensively examined the influence of WNT on the A/P positional identity of hPSC-derived NPCs and neurons. To date, most studies have relied on FGF8 (Yan et al., 2005; Yang et al., 2008) or retinoic
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Introduction The p functions are ubiquitously altered
2018-11-02

Introduction The p53 functions are ubiquitously altered in cancer cells by mutations/perturbation of its signaling pathways, and loss of p53 activity is a prerequisite for cancer development. Mutant p53 is thought to play a pivotal role in promoting invasion, favoring cancer cell exit from the pri
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Here we provide the first definitive evidence
2018-11-02

Here we provide the first definitive evidence that an alternative airway progenitor cell, marked by expression of SOX2, is the predominant cell of origin for nascent KRT5+ wnt signaling pathway after influenza infection. This was true for nascent KRT5+ cells that emerge in the airways and those that
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br The function r is determined from the integral equation
2018-11-02

The function β (r) is determined from the integral equation the core of which has the form In the case when 0, the formulae (4) are transformed into the known Terezawa\'s solution [9]. Concentrated force applied to an elastically fixed boundary of the half-space For the transition in the s
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Relying on more advanced statistical
2018-11-02

Relying on more advanced statistical techniques, the second approach offers a number of analytic advantages. It moves beyond observed combinations of behaviour, to identify latent (or unobservable) types either of participants based on their behaviours (e.g. latent class analysis) or of behaviours (
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While the preponderance of evidence thus far has
2018-11-02

While the preponderance of evidence thus far has linked religiosity and health in a positive way, effects are not universally beneficial. Certain aspects and measures of religiosity have been shown to be disadvantages to health. For instance, religion has been found to induce anxiety when it histam
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OSA is a common sleep disordered breathing
2018-11-01

OSA is a common sleep disordered breathing, characterized by recurrent apneas (complete breathing cessation) or hypopneas (shallow breathing), upper airway constriction, hypoxemia, hypercapnia, autonomic activation, and EEG arousal and sleep fragmentation, leading to daytime fatigue and sleepiness [
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br Acknowledgements The research work
2018-11-01

Acknowledgements The research work has been fully supported by the Higher Education Commission, Pakistan with Support initiative Grant No. IRSIP 21 Ps 04. I would like to thank the Department of Applied sciences of UWE, Bristol,UK for providing access to their lab facilities. Introduction Th
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This article demonstrates the sensitive detection and quanti
2018-11-01

This article demonstrates the sensitive detection and quantification of C-reactive protein (CRP) using the designed MCFOB and an adaptive sandwich immunoassay [8,18,19]. The normal level of CRP in blood serum is 640ng/ml, but tends to slightly increase with age [13]. High concentrations of CRP are a
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br Introducci n br El funcionamiento tradicional de la
2018-11-01

Introducción El funcionamiento tradicional de la banca: actividades y estructuras de ingresos La primera observación es que cambió drásticamente la estructura de los bancos, particularmente la composición de sus activos, pasivos e ingresos en el periodo de dominación del capital financiero. Co
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Ola financiera UNAM br Momento Econ
2018-11-01

Ola financiera UNAM Momento Económico UNAM Arturo Huerta González, Otra vez el nulo crecimiento y César Armando Salazar, La economía mexicana: entre choques externos y la debilidad del mercado interno; en conjunto nos muestran las perspectivas de crecimiento para la economía mexicana al finaliza
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Our previous studies demonstrated that statins containing ca
2018-11-01

Our previous studies demonstrated that statins containing carboxylic Go 6976 chains also had activity against histone deacetylase (HDAC), an important oncoprotein, to exert anti-cancer effects. Thus, statins may suppress tumor formation through the inhibition of both HMGR and HDAC activity (Lin et a
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Protein tyrosine phosphatases PTPs are inactivated by
2018-11-01

Protein tyrosine phosphatases (PTPs) are inactivated by ROS-catalyzed sulfenylation at the conserved motif HC(X)5RS/T, since this motif overlaps with the substrate binding site of PTPs and this sulfenylation interrupts the binding with substrate (Fig. 4E). PP2Ac has a motif of HC(X)4EXV that is simi
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Multiple physiological mechanisms by which
2018-11-01

Multiple physiological mechanisms by which enteropathogens can disrupt gut functioning have been identified (Guerrant et al., 1999; Berkes et al., 2003; Beltinger et al., 2008; Viswanathan et al., 2009; Kamada et al., 2013; Brown et al., 2015) although the long term consequences in settings where ex
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