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IGF signaling has been shown to induce chromatin
2024-12-18
IGF-1 signaling has been shown to induce N1-Methyl-ATP synthesis changes via interacting with MKK-p38 signaling (Serra et al., 2007) and by perturbing Foxo3a signaling (Stitt et al., 2004), among other mechanisms. The current study demonstrates that the acetyl group itself may be limiting, since IGF
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ERβ in cancer therapy Later on Wayner Burton Ingold Barclay
2024-12-17
Later on, Wayner, Burton, Ingold, Barclay, and Locke (1987) modified the method by using lipid to examine the ability of an antioxidant ERβ in cancer therapy protect against lipid peroxidation generated by azo-compound. It was later improved using β-phycoerythrin (β-PE) as a fluorescent probe, and
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76 2 australia It has been proposed that a PrP pathogenic
2024-12-17
It has been proposed that a PrP pathogenic mechanism is a toxic gain of function secondary to the misfolding of mutated PrP. However, such a mechanism might not apply to all mutant PrP species, since some mutations had little effect on the stability and folding kinetics of PrP (Swietnicki et al., 19
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br Concluding Remarks and Future Perspectives Fluorescent
2024-12-17
Concluding Remarks and Future Perspectives Fluorescent eukaryotic initiation factor have helped researchers to elucidate antibiotic MOA and off-target interactions, to screen for new antibiotics, to detect antibiotics in the environment, to track antibiotic uptake throughout cells and organisms,
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AR is expressed in cell specific human ovarian follicles at
2024-12-17
AR is expressed in cell-specific human ovarian follicles at all stages of follicular development [25]. Administration of androgens in animals demonstrated initiation of follicular recruitment, stimulation of early stages of follicular growth, and increase in the number of growing follicles [26,27].
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In our previous study we showed that normal and cancerous
2024-12-17
In our previous study we showed that normal and cancerous NKY 80 mg of kidney exhibit the activity of alcohol dehydrogenase and aldehyde dehydrogenase. Furthermore, the activity of class I ADH isoenzymes and total ADH were significantly higher in cancer tissue than in unchanged renal cells. Moreover
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We stimulated HNEpC cells with LPS found
2024-12-17
We stimulated HNEpC cells with LPS found that the secretion of inflammatory cytokines and the expression of AHR was increased significantly, and miR124 was reduced. It has been found that LPS as a foreign substance can bind to the TLR family of proteins to activate intracellular AHR signaling [[19],
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S3I-201 A previous study reported that the serotonergic mech
2024-12-17
A previous study reported that the serotonergic mechanism was involved in the psychological stress-induced alteration in synaptic plasticity in the rat hippocampal CA1 field (Matsumoto et al., 2004). Sumitaka Inoue et al. (Inoue et al., 2014) reported that pretreatment with a 5-HT1A receptor partial
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It is important to note that stable
2024-12-17
It is important to note that stable amnesia is, apparently, a general biological phenomenon and can be found in different animal species. In studies on rats, it was found that if reconsolidation of conditioned olfactory aversion memory was impaired by the antagonist of NMDA glutamate receptors, amne
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Our second patient years old male
2024-12-17
Our second patient, 42years old male, a farmer, was all right when he went to sleep, but noticed drooping of eyelids and swallowing difficulty when he woke up. He later developed flaccid weakness of all four limbs and was quadriplegic when he was wheeled into the emergency room. He was tachypneic an
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In the U S surveillance of
2024-12-17
In the U.S., surveillance of ACEs has garnered traction at the state level through administration of the ACE Optional Module in CDC’s Behavioral Risk Factor Surveillance System (BRFSS) (Centers for Disease Control & Prevention, 2003). Since 2009, select states have implemented the ACEs optional modu
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The following are the supplementary data related to
2024-12-17
The following are the supplementary data related to this article. Conflict of interest Acknowledgements Disclosure of interest Introduction Since the introduction of platinum-based chemotherapy, metastatic testicular cancer has become a curable disease and most testicular cancer patient
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Regarding androgens it is known that they are also
2024-12-17
Regarding androgens, it is known that they are also essential for reproductive success (Walters et al., 2010). At the molecular level, their effects are produced mainly by dihydrotestosterone (DHT), arising from the conversion of testosterone by the enzyme 3-oxo-5-alpha-steroid-4-dehydrogenase (enco
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Axl has been reported to mediate cell cell adhesion
2024-12-17
Axl has been reported to mediate cell-cell adhesion and sphere-growth [11], [18] and to be important for metastasis to secondary organs [12], [14], [20]. We found an Axl-dependent CCRCC-ability of sphere-formation and repopulation after non-adhesive growth. Axl-inhibited cells could not attach to ea
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br Materials and methods br Results To explore the potential
2024-12-17
Materials and methods Results To explore the potential role of autophagy in drug resistance, we firstly performed immunohistochemistry to compare the B cell expansion co-culture of p62 in paired primary, metastatic, and recurrent tumor tissues from 26 ovarian cancer patients. The expression o
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